APOBR - apolipoprotein B receptor Gene

Homo sapiens

Also known as APOB48R; APOB100R

Gene ID: 55911 | Gene type: protein coding

About APOBR

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:28,494,643-28,498,964 (from NCBI)

This gene has 1 transcript (splice variant) and 82 orthologues. Biased expression in colon (RPKM 19.1), spleen (RPKM 14.5) and 12 other tissues.

Summary

Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble Vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008]

APOBR Products(1)

mRNA	Protein	Name
NM_018690.4	NP_061160.3	apolipoprotein B receptor

Protein Preferred Names

Protein Names

apolipoprotein B receptor

apoB-48R

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00843	APOBR Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	APOBR	RGD	RGD:1565169
Canis familiaris	APOBR	VGNC	VGNC:37998
Macaca mulatta	APOBR	VGNC	VGNC:69892
Mus musculus	APOBR	MGD	MGI:2176230
Bos taurus	APOBR	VGNC	VGNC:26030

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