2. Gene
  3. Cyp39a1 - cytochrome P450, family 39, subfamily a, polypeptide 1 Gene

Cyp39a1 - cytochrome P450, family 39, subfamily a, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mCYP39A1

Gene ID: 56050 | Gene type: protein coding

About Cyp39a1

Summary

Enables oxysterol 7-alpha-hydroxylase activity and steroid 7-alpha-hydroxylase activity. Involved in bile acid biosynthetic process. Acts upstream of or within Cholesterol catabolic process. Predicted to be located in intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human CYP39A1 (Cytochrome P450 family 39 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp39a1 Products(3)

mRNA Protein Name
NM_001285947.1 NP_001272876.1 24-hydroxycholesterol 7-alpha-hydroxylase isoform 2
NM_001285948.1 NP_001272877.1 24-hydroxycholesterol 7-alpha-hydroxylase isoform 3
NM_018887.4 NP_061375.1 24-hydroxycholesterol 7-alpha-hydroxylase isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables oxysterol 7-alpha-hydroxylase activity IDA
IDA: Inferred from direct assay
10748047 MGI
enables steroid 7-alpha-hydroxylase activity IDA
IDA: Inferred from direct assay
10748047 MGI
Biological Process GO Annotation Evidence Reference Source
involved in bile acid biosynthetic process IDA
IDA: Inferred from direct assay
10748047 MGI
acts upstream of or within cholesterol catabolic process IDA
IDA: Inferred from direct assay
10748047 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

24-hydroxycholesterol 7-alpha-hydroxylase

cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase)

oxysterol 7-alpha-hydroxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03470 CYP39A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp39a1 NCBI NCBI:51302