Psmg1 - proteasome (prosome, macropain) assembly chaperone 1 Gene

Mus musculus

Also known as Dscr2

Gene ID: 56088 | Gene type: protein coding

About Psmg1

Summary

Enables Proteasome binding activity. Acts upstream of or within cerebellar granule cell precursor proliferation and Proteasome core complex assembly. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of chaperone complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human PSMG1 (Proteasome assembly chaperone 1). [provided by Alliance of Genome Resources, Apr 2022]

Psmg1 Products(1)

mRNA	Protein	Name
NM_019537.3	NP_062410.1	proteasome assembly chaperone 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables proteasome binding	IDA IDA: Inferred from direct assay	20498273	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cerebellar granule cell precursor proliferation	IMP IMP: Inferred from mutant phenotype	20498273	MGI
acts upstream of or within proteasome core complex assembly	IMP IMP: Inferred from mutant phenotype	20498273	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

proteasome assembly chaperone 1

Down syndrome critical region homolog 2

down syndrome critical region protein 2 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11336	PSMG1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Psmg1	NCBI	NCBI:8624

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