2. Gene
  3. PSMG1 - proteasome assembly chaperone 1 Gene

PSMG1 - proteasome assembly chaperone 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PAC1; DSCR2; PAC-1; C21LRP; LRPC21

Gene ID: 8624 | Gene type: protein coding

About PSMG1

Cytogenetic location: 21q22.2 Genomic coordinates (GRCh38): 21:39,174,769-39,183,514 (from NCBI)

This gene has 5 transcripts (splice variants) and 193 orthologues. Broad expression in testis (RPKM 57.7), thyroid (RPKM 14.4) and 23 other tissues.

Summary

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nucleoplasm. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

PSMG1 Products(4)

mRNA Protein Name
NM_001261824.1 NP_001248753.1 proteasome assembly chaperone 1 isoform 3
NM_001320795.1 NP_001307724.1 proteasome assembly chaperone 1 isoform d
NM_003720.4 NP_003711.1 proteasome assembly chaperone 1 isoform a
NM_203433.2 NP_982257.1 proteasome assembly chaperone 1 isoform b
Protein Preferred Names Protein Names

proteasome assembly chaperone 1

Down syndrome critical region gene 2

Related Diseases

Diseases Alias
Down Syndrome

Trisomy 21

Complete Trisomy 21 Syndrome

Down'S Syndrome

Trisomy 21 Syndrome

Down'S Syndrome - Trisomy 21

Downs Syndrome

G Trisomy

47,Xx,+21

47,Xy,+21

Trisomy G

Down Syndrome, Susceptibility To

Chromosome 21 Trisomy

Trisomy 21 Nos

Abnormal Autosomes 21
Thrombasthenia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11336 PSMG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PSMG1 RGD RGD:1305454
Bos taurus PSMG1 VGNC VGNC:33478
Mus musculus PSMG1 MGD MGI:1860263
Macaca mulatta PSMG1 VGNC VGNC:76347
Canis familiaris PSMG1 VGNC VGNC:45121
Felis catus PSMG1 VGNC VGNC:102810