Tamalin - trafficking regulator and scaffold protein tamalin Gene

Also Known as Grasp

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56149

Summary

Predicted to enable PDZ domain binding activity; identical protein binding activity; and small GTPase binding activity. Involved in regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane. Acts upstream of or within signal transduction. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Orthologous to human TAMALIN (trafficking regulator and scaffold protein tamalin). [provided by Alliance of Genome Resources, Apr 2022]

Tamalin Products (1)

mRNA Protein Name
NM_019518.3 NP_062391.3 general receptor for phosphoinositides 1-associated scaffold protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10828067 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
32376687 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
32376687 MGI
acts upstream of or within signal transduction IPI
IPI: Inferred from physical interaction
10828067 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
32376687 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
32376687 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10828067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

general receptor for phosphoinositides 1-associated scaffold protein

  • GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

  • GRP1-associated scaffold protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14192 TAMALIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tamalin NCBI NCBI:160622