2. Gene
  3. TAMALIN - trafficking regulator and scaffold protein tamalin Gene

TAMALIN - trafficking regulator and scaffold protein tamalin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GRASP

Gene ID: 160622 | Gene type: protein coding

About TAMALIN

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,006,946-52,015,889 (from NCBI)

This gene has 8 transcripts (splice variants), 185 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 8.3), fat (RPKM 7.8) and 23 other tissues.

Summary

This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 Metabotropic Glutamate Receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]

TAMALIN Products(2)

mRNA Protein Name
NM_001271856.2 NP_001258785.1 protein TAMALIN isoform 2
NM_181711.4 NP_859062.1 protein TAMALIN isoform 1

TAMALIN Protein Structure

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (102 - 185)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
Protein Preferred Names Protein Names

protein TAMALIN

GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

Related Diseases

Diseases Alias
Schizophrenia 6

SCZD6

Schizophrenia Susceptibility Locus, Chromosome 8p-Related

Schizophrenia, Type 6
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14192 TAMALIN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TAMALIN RGD RGD:70554
Macaca mulatta TAMALIN VGNC VGNC:72966
Mus musculus TAMALIN MGD MGI:1860303
Bos taurus TAMALIN VGNC VGNC:29628