Ptbp2 - polypyrimidine tract binding protein 2 Gene

Also Known as Ptb2; nPTB; brPTB

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56195

Summary

Enables mRNA binding activity. Acts upstream of or within mRNA splice site selection and regulation of neural precursor cell proliferation. Part of spliceosomal complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PTBP2 (polypyrimidine tract binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ptbp2 Products (2)

mRNA Protein Name
NM_001310711.1 NP_001297640.1 polypyrimidine tract-binding protein 2 isoform 2
NM_019550.2 NP_062423.1 polypyrimidine tract-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
10829067 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10829067 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within mRNA splice site recognition IDA
IDA: Inferred from direct assay
10829067 MGI
acts upstream of or within mRNA splice site recognition IMP
IMP: Inferred from mutant phenotype
22802532 MGI
acts upstream of or within regulation of neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
22802532 MGI
Cellular Component GO Annotation Evidence References Source
part of spliceosomal complex IDA
IDA: Inferred from direct assay
10829067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polypyrimidine tract-binding protein 2

  • RRM-type RNA-binding protein brPTB

  • brain-enriched PTB

  • brain-enriched polypyrimidine tract-binding protein

  • neural polypyrimidine tract-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11352 PTBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptbp2 NCBI NCBI:58155