Rassf1 - Ras association (RalGDS/AF-6) domain family member 1 Gene

Also Known as 123F2; RDA32; NORE2A; REH3P21; Rassf1A; Rassf1B; Rassf1C

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56289

Summary

Enables small GTPase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; positive regulation of protein ubiquitination; and protein stabilization. Predicted to be located in cytoplasm and microtubule. Predicted to be active in microtubule Cytoskeleton and nucleus. Is expressed in liver and metanephros. Human ortholog(s) of this gene implicated in breast cancer; reproductive organ Cancer (multiple); transitional cell carcinoma; and urinary system Cancer (multiple). Orthologous to human RASSF1 (Ras association domain family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Rassf1 Products (6)

mRNA Protein Name
NM_001243748.2 NP_001230677.1 ras association domain-containing protein 1 isoform 1
NM_001411798.1 NP_001398727.1 ras association domain-containing protein 1 isoform 3
NM_001411799.1 NP_001398728.1 ras association domain-containing protein 1 isoform 4
NM_001411800.1 NP_001398729.1 ras association domain-containing protein 1 isoform 4
NM_001411801.1 NP_001398730.1 ras association domain-containing protein 1 isoform 4
NM_019713.5 NP_062687.1 ras association domain-containing protein 1 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17335777 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
23294242 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras association domain-containing protein 1

  • 123F protein

  • RASSF1A tumor suppressor

  • Ras association (RalGDS/AF-6) domain family 1

  • protein 123F2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-112288 C188-9 99.84% Phase 2

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11701 RASSF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rassf1 NCBI NCBI:11186