CFAP298 - cilia and flagella associated protein 298 Gene

Also Known as Kur; FBB18; CILD26; DNAAF16; C21orf48; C21orf59

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 56683

Summary

This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Naturally occuring readthrough transcription occurs from this locus to the downstream t-complex 10 like (TCP10L) gene. [provided by RefSeq, Apr 2017]

CFAP298 Products (1)

mRNA Protein Name
NM_017835.1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
24094744 GOA
involved in regulation of cilium movement IGI
IGI: Inferred from genetic interaction
24094744 GOA
involved in regulation of cilium movement IMP
IMP: Inferred from mutant phenotype
24094744 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cilia- and flagella-associated protein 298

  • UPF0769 protein C21orf59

  • dynein axonemal assembly factor 16

  • kurly homolog

  • prostate cancer upregulated protein 1

  • protein kurly homolog

CFAP298 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CFAP298 P57076 PEX7 Homo sapiens O00628
Anti Tag CoIP
33961781
Intra
CFAP298 P57076 PEX7 Homo sapiens O00628
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction