2. Gene
  3. Akap10 - A kinase (PRKA) anchor protein 10 Gene

Akap10 - A kinase (PRKA) anchor protein 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PRKA10; D-AKAP2; D-AKAP-2; 1500031L16Rik; B130049N18Rik

Gene ID: 56697 | Gene type: protein coding

About Akap10

Summary

This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. It has been reported that this protein is important for maintaining heart rate and myocardial contractility through its targeting of protein kinase A. In mouse, defects of this gene lead to cardiac arrhythmias and premature death. In humans, polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2013]

Akap10 Products(1)

mRNA Protein Name
NM_019921.3 NP_064305.2 A-kinase anchor protein 10, mitochondrial precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within protein localization IDA
IDA: Inferred from direct assay
11248059 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
11248059 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 10, mitochondrial

dual specificity A kinase-anchoring protein 2

protein kinase A-anchoring protein 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00513 AKAP10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap10 NCBI NCBI:11216