Plag1 - pleiomorphic adenoma gene 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56711

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; positive regulation of gene expression; and positive regulation of glial cell proliferation. Acts upstream of or within gland morphogenesis and prostate gland growth. Predicted to be located in centrosome; cytosol; and nuclear speck. Is expressed in several structures, including brain; embryo ectoderm; genitourinary system; limb bud; and sensory organ. Human ortholog(s) of this gene implicated in Silver-Russell syndrome and pleomorphic adenoma. Orthologous to human PLAG1 (PLAG1 zinc finger). [provided by Alliance of Genome Resources, Apr 2022]

Plag1 Products (1)

mRNA Protein Name
NM_019969.3 NP_064353.2 zinc finger protein PLAG1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within gland morphogenesis IMP
IMP: Inferred from mutant phenotype
15606491 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
15606491 MGI
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
19808959 MGI
acts upstream of or within organ growth IMP
IMP: Inferred from mutant phenotype
15606491 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
19808959 MGI
involved in positive regulation of glial cell proliferation IDA
IDA: Inferred from direct assay
19808959 MGI
acts upstream of or within prostate gland growth IMP
IMP: Inferred from mutant phenotype
15606491 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein PLAG1

  • C2H2 zinc finger protein PLAG1

  • pleiomorphic adenoma gene 1 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10643 PLAG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21690 Plag1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28208 Plag1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plag1 NCBI NCBI:5324