Psrc1 - proline/serine-rich coiled-coil 1 Gene

Also Known as Dda3; 5430413I02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56742

Summary

Enables microtubule binding activity. Involved in several processes, including microtubule bundle formation; positive regulation of microtubule polymerization; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm; midbody; and spindle. Is expressed in several structures, including brain ventricular layer; lung; rest of cerebellum marginal layer; submandibular gland primordium; and thymus primordium. Orthologous to human PSRC1 (proline and serine rich coiled-coil 1). [provided by Alliance of Genome Resources, Apr 2022]

Psrc1 Products (2)

mRNA Protein Name
NM_001190161.1 NP_001177090.1 proline/serine-rich coiled-coil protein 1
NM_019976.3 NP_064360.1 proline/serine-rich coiled-coil protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
17310996 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17310996 MGI
Biological Process GO Annotation Evidence References Source
involved in microtubule bundle formation IDA
IDA: Inferred from direct assay
17310996 MGI
involved in negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
10618717 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
17310996 MGI
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
17310996 MGI
involved in positive regulation of microtubule polymerization IDA
IDA: Inferred from direct assay
17310996 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10618717 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
17310996 MGI
located in midbody IDA
IDA: Inferred from direct assay
17310996 MGI
located in spindle IDA
IDA: Inferred from direct assay
17310996 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline/serine-rich coiled-coil protein 1

  • differential display and activated by p53

  • p53-regulated DDA3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11343 PSRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psrc1 NCBI NCBI:84722