KCNIP2 - Kcnip2 potassium voltage-gated channel interacting protein 2 Gene

Rattus norvegicus

Also known as Kchip2

Gene ID: 56817 | Gene type: protein coding

About KCNIP2

Summary

Enables calcium ion binding activity and Potassium Channel regulator activity. Involved in clustering of voltage-gated potassium channels and regulation of potassium ion transmembrane transport. Located in dendrite and plasma membrane. Part of voltage-gated Potassium Channel complex. Orthologous to human KCNIP2 (potassium voltage-gated channel interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

KCNIP2 Products(3)

mRNA	Protein	Name
NM_001033961.1	NP_001029133.1	Kv channel-interacting protein 2 isoform c
NM_020094.2	NP_064479.2	Kv channel-interacting protein 2 isoform a
NM_020095.2	NP_064480.2	Kv channel-interacting protein 2 isoform b

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables calcium ion binding	IDA IDA: Inferred from direct assay	12006572	RGD
enables potassium channel regulator activity	IDA IDA: Inferred from direct assay	12967630	RGD
enables potassium channel regulator activity	IMP IMP: Inferred from mutant phenotype	12006572	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	15356203	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	15356203	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in clustering of voltage-gated potassium channels	IDA IDA: Inferred from direct assay	12967630	RGD
involved in clustering of voltage-gated potassium channels	IMP IMP: Inferred from mutant phenotype	12006572	RGD
involved in regulation of potassium ion transmembrane transport	IDA IDA: Inferred from direct assay	16820361	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	15356203	RGD
located in plasma membrane	IDA IDA: Inferred from direct assay	16820361	RGD
part of voltage-gated potassium channel complex	IDA IDA: Inferred from direct assay	15356203	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

Kv channel-interacting protein 2

A-type potassium channel modulatory protein 2	Kv channel-interacting protein 2-like
potassium channel auxiliary subunit KCHIP2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07133	KCNIP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	KCNIP2	NCBI	NCBI:30819

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