Haao - 3-hydroxyanthranilate 3,4-dioxygenase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56823

Summary

Enables 3-hydroxyanthranilate 3,4-dioxygenase activity; iron ion binding activity; and oxygen binding activity. Involved in quinolinate metabolic process. Located in mitochondrial membrane. Used to study Huntington's disease. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Haao Products (1)

mRNA Protein Name
NM_020076.2 NP_064461.1 3-hydroxyanthranilate 3,4-dioxygenase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 3-hydroxyanthranilate 3,4-dioxygenase activity IDA
IDA: Inferred from direct assay
2940338 RGD
enables iron ion binding IDA
IDA: Inferred from direct assay
2940338 RGD
enables oxygen binding IDA
IDA: Inferred from direct assay
9870556 RGD
Biological Process GO Annotation Evidence References Source
involved in quinolinate metabolic process IDA
IDA: Inferred from direct assay
2940338 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
3346732 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-hydroxyanthranilate 3,4-dioxygenase

  • 3-HAO

  • 3-hydroxyanthranilate oxygenase

  • 3-hydroxyanthranilic acid dioxygenase

  • HAD

Recombinant Haao Proteins

Cat. No. Product Name Accession Purity
HY-P76963 HAAO Protein, Rat (His) P46953 (M1-G286) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05981 HAAO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19904 Haao Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26405 Haao Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Haao NCBI NCBI:23498