FSTL5 - follistatin like 5 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56884

About FSTL5

This gene has 5 transcripts (splice variants), 211 orthologues and 6 paralogues. Biased expression in brain (RPKM 6.2), adrenal (RPKM 3.7) and 1 other tissue.

Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in cell differentiation. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

FSTL5 Products (3)

mRNA Protein Name
NM_001128427.3 NP_001121899.1 follistatin-related protein 5 isoform b precursor
NM_001128428.3 NP_001121900.1 follistatin-related protein 5 isoform c precursor
NM_020116.5 NP_064501.2 follistatin-related protein 5 isoform a precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24407287 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FSTL5 Protein Structure

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (93 - 133)

Ig_2

Ig_2: Immunoglobulin domain (258 - 339)

I-set

I-set: Immunoglobulin I-set domain (341 - 430)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 847 a.a.
Protein Preferred Names Protein Names

follistatin-related protein 5

  • follistatin-like protein 5

Recombinant FSTL5 Proteins

Cat. No. Product Name Accession Purity
HY-P76350 FSTL5 Protein, Human (HEK293, Fc) Q8N475-1 (R21-A847) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P76351 FSTL5 Protein, Human (HEK293, His) Q8N475-1 (R21-A847) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Clubfoot

  • Congenital Talipes Equinovarus

  • Congenital Clubfoot

  • Congenital Equinovarus

  • Equinovarus Deformity Of Foot

  • Club Foot
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05131 FSTL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20931 Fstl5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27448 Fstl5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FSTL5 RGD RGD:1306858
Canis familiaris FSTL5 VGNC VGNC:41001
Felis catus FSTL5 VGNC VGNC:78499
Mus musculus FSTL5 MGD MGI:2442179
Macaca mulatta FSTL5 VGNC VGNC:72758
Bos taurus FSTL5 VGNC VGNC:106748
Others FSTL5 NCBI