Kcne3 - potassium voltage-gated channel, Isk-related subfamily, gene 3 Gene

Also Known as MiRP2; 2210017H05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57442

Summary

Predicted to enable Potassium Channel activity; Potassium Channel regulator activity; and transmembrane transporter binding activity. Predicted to contribute to delayed rectifier Potassium Channel activity and voltage-gated Potassium Channel activity involved in ventricular cardiac muscle cell action potential repolarization. Involved in cellular chloride ion homeostasis; potassium ion transmembrane transport; and sodium ion transport. Is active in basolateral part of cell. Is expressed in several structures, including branchial arch; ear; forelimb bud; gut; and heart. Human ortholog(s) of this gene implicated in Brugada syndrome 6 and hypokalemic periodic paralysis. Orthologous to human KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcne3 Products (7)

mRNA Protein Name
NM_001190869.1 NP_001177798.1 potassium voltage-gated channel subfamily E member 3
NM_001190870.1 NP_001177799.1 potassium voltage-gated channel subfamily E member 3
NM_001190871.2 NP_001177800.1 potassium voltage-gated channel subfamily E member 3
NM_001190950.1 NP_001177879.1 potassium voltage-gated channel subfamily E member 3
NM_001360466.1 NP_001347395.1 potassium voltage-gated channel subfamily E member 3
NM_001360467.1 NP_001347396.1 potassium voltage-gated channel subfamily E member 3
NM_020574.5 NP_065599.1 potassium voltage-gated channel subfamily E member 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19623261 MGI
Biological Process GO Annotation Evidence References Source
involved in intracellular chloride ion homeostasis IDA
IDA: Inferred from direct assay
11527966 MGI
involved in intracellular chloride ion homeostasis IMP
IMP: Inferred from mutant phenotype
11527966 MGI
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
11527966 MGI
involved in potassium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
11527966 MGI
involved in sodium ion transport IDA
IDA: Inferred from direct assay
11527966 MGI
involved in sodium ion transport IMP
IMP: Inferred from mutant phenotype
11527966 MGI
Cellular Component GO Annotation Evidence References Source
is active in basolateral part of cell IDA
IDA: Inferred from direct assay
11527966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily E member 3

  • minK-related peptide 2

  • minimum potassium ion channel-related peptide 2

  • potassium channel subunit beta MiRP2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-142991 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol / Unkown
HY-RS07117 KCNE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcne3 NCBI NCBI:10008