Tacc2 - transforming, acidic coiled-coil containing protein 2 Gene

Mus musculus

Also known as mKIAA4180

Gene ID: 57752 | Gene type: protein coding

About Tacc2

Summary

This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Tacc2 Products(4)

mRNA	Protein	Name
NM_001004468.3	NP_001004468.1	transforming acidic coiled-coil-containing protein 2 isoform c
NM_001347637.2	NP_001334566.1	transforming acidic coiled-coil-containing protein 2 isoform d
NM_021314.5	NP_067289.2	transforming acidic coiled-coil-containing protein 2 isoform b
NM_206856.4	NP_996738.2	transforming acidic coiled-coil-containing protein 2 isoform a

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	17920017	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within astral microtubule organization	IDA IDA: Inferred from direct assay	17920017	MGI
acts upstream of or within cell population proliferation	IMP IMP: Inferred from mutant phenotype	17920017	MGI
acts upstream of or within cerebral cortex development	IMP IMP: Inferred from mutant phenotype	17920017	MGI
acts upstream of or within interkinetic nuclear migration	IMP IMP: Inferred from mutant phenotype	17920017	MGI
acts upstream of or within microtubule cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	17920017	MGI
acts upstream of or within neurogenesis	IMP IMP: Inferred from mutant phenotype	17920017	MGI
acts upstream of or within regulation of microtubule-based process	IMP IMP: Inferred from mutant phenotype	17920017	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transforming acidic coiled-coil-containing protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14140	TACC2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tacc2	NCBI	NCBI:10579

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