Tacc2 - transforming, acidic coiled-coil containing protein 2 Gene

Also Known as mKIAA4180

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57752

Summary

This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Tacc2 Products (4)

mRNA Protein Name
NM_001004468.3 NP_001004468.1 transforming acidic coiled-coil-containing protein 2 isoform c
NM_001347637.2 NP_001334566.1 transforming acidic coiled-coil-containing protein 2 isoform d
NM_021314.5 NP_067289.2 transforming acidic coiled-coil-containing protein 2 isoform b
NM_206856.4 NP_996738.2 transforming acidic coiled-coil-containing protein 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
17920017 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within astral microtubule organization IDA
IDA: Inferred from direct assay
17920017 MGI
acts upstream of or within cell population proliferation IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within interkinetic nuclear migration IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within neurogenesis IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within regulation of microtubule-based process IMP
IMP: Inferred from mutant phenotype
17920017 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transforming acidic coiled-coil-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14140 TACC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tacc2 NCBI NCBI:10579