Rangrf - RAN guanine nucleotide release factor Gene

Also Known as Mog1; Rangnrf; 2400006H24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57785

Summary

Enables several functions, including guanyl-nucleotide exchange factor activity; small GTPase binding activity; and transmembrane transporter binding activity. Involved in regulation of membrane depolarization and regulation of sodium ion transmembrane transporter activity. Located in intercalated disc and nucleoplasm. Is expressed in central nervous system; retina; retina ganglion cell layer; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human RANGRF (RAN guanine nucleotide release factor). [provided by Alliance of Genome Resources, Apr 2022]

Rangrf Products (4)

mRNA Protein Name
NM_001285441.1 NP_001272370.1 ran guanine nucleotide release factor isoform 1
NM_001285442.1 NP_001272371.1 ran guanine nucleotide release factor isoform 3
NM_001285443.1 NP_001272372.1 ran guanine nucleotide release factor isoform 4
NM_021329.3 NP_067304.1 ran guanine nucleotide release factor isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
10811801 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
10811801 MGI
enables sodium channel regulator activity IMP
IMP: Inferred from mutant phenotype
23420830 MGI
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
18184654 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of membrane depolarization IMP
IMP: Inferred from mutant phenotype
23420830 MGI
involved in regulation of sodium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
23420830 MGI
involved in regulation of sodium ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
23420830 MGI
Cellular Component GO Annotation Evidence References Source
located in intercalated disc IDA
IDA: Inferred from direct assay
18184654 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
10811801 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ran guanine nucleotide release factor

  • ran-binding protein MOG1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11651 RANGRF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rangrf NCBI NCBI:29098