Myot - myotilin Gene

Also Known as Ttid; 5530402I04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58916

Summary

Predicted to enable alpha-actinin binding activity and cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Located in Z disc. Is expressed in several structures, including embryo mesenchyme; gut; lung; mesonephros; and nervous system. Human ortholog(s) of this gene implicated in muscular dystrophy; myofibrillar myopathy 3; and spheroid body myopathy. Orthologous to human MYOT (myotilin). [provided by Alliance of Genome Resources, Apr 2022]

Myot Products (1)

mRNA Protein Name
NM_001033621.4 NP_001028793.1 myotilin

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
19047374 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myotilin

  • myofibrillar titin-like Ig domains protein

  • titin immunoglobulin domain protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08964 MYOT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myot NCBI NCBI:9499