Myoz1 - myozenin 1 Gene

Also Known as FATZ; Myoz; 2310001N11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 59011

Summary

Enables protein serine/threonine Phosphatase Inhibitor activity. Involved in several processes, including negative regulation of calcineurin-NFAT signaling cascade; negative regulation of skeletal muscle tissue regeneration; and sarcomere organization. Acts upstream of or within with a positive effect on skeletal muscle fiber adaptation. Located in actin Cytoskeleton. Is expressed in diaphragm; heart; musculature; and tongue. Orthologous to human MYOZ1 (myozenin 1). [provided by Alliance of Genome Resources, Apr 2022]

Myoz1 Products (1)

mRNA Protein Name
NM_021508.3 NP_067483.1 myozenin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11114196 MGI
enables protein serine/threonine phosphatase inhibitor activity IMP
IMP: Inferred from mutant phenotype
18846255 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of calcineurin-NFAT signaling cascade IMP
IMP: Inferred from mutant phenotype
18846255 MGI
involved in negative regulation of skeletal muscle tissue regeneration IMP
IMP: Inferred from mutant phenotype
18846255 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18846255 MGI
involved in sarcomere organization IMP
IMP: Inferred from mutant phenotype
18846255 MGI
acts upstream of or within positive effect skeletal muscle fiber adaptation IMP
IMP: Inferred from mutant phenotype
18846255 MGI
involved in skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
18846255 MGI
involved in wound healing IMP
IMP: Inferred from mutant phenotype
18846255 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
11114196 MGI
located in actin cytoskeleton IPI
IPI: Inferred from physical interaction
11114196 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myozenin-1

  • calcineurin-2

  • calsarcin-2

  • filamin-, actinin- and telethonin-binding protein

  • skeletal muscle-specific protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08965 MYOZ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myoz1 NCBI NCBI:58529