2. Gene
  3. Fxyd6 - FXYD domain-containing ion transport regulator 6 Gene

Fxyd6 - FXYD domain-containing ion transport regulator 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Php; 0610030I18Rik

Gene ID: 59095 | Gene type: protein coding

About Fxyd6

Summary

This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved Amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, Fxyd6, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., [email protected]., Jul 2006]

Fxyd6 Products(1)

mRNA Protein Name
NM_022004.6 NP_071287.1 FXYD domain-containing ion transport regulator 6 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
24413018 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24413018 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
24413018 MGI
is active in postsynaptic membrane EXP
EXP: Inferred from Experiment
24413018 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
24413018 MGI
is active in postsynaptic membrane IEP
IEP: Inferred from expression pattern
24413018 MGI
is active in presynaptic membrane EXP
EXP: Inferred from Experiment
24413018 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
24413018 MGI
is active in presynaptic membrane IEP
IEP: Inferred from expression pattern
24413018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FXYD domain-containing ion transport regulator 6

PLM-like protein

phosphohippolin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05170 FXYD6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fxyd6 NCBI NCBI:53826