2. Gene
  3. Lin7c - lin-7 homolog C, crumbs cell polarity complex component Gene

Lin7c - lin-7 homolog C, crumbs cell polarity complex component Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Veli3; MALS-3

Gene ID: 60442 | Gene type: protein coding

About Lin7c

Summary

Enables PDZ domain binding activity. Predicted to be involved in several processes, including maintenance of epithelial cell apical/basal polarity; morphogenesis of an epithelial sheet; and protein localization to basolateral plasma membrane. Located in cell-cell junction. Is active in glutamatergic synapse. Orthologous to human LIN7C (lin-7 homolog C, crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]

Lin7c Products(1)

mRNA Protein Name
NM_021851.2 NP_068623.1 protein lin-7 homolog C
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
15024025 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
10362251 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
10362251 RGD
is active in synapse IDA
IDA: Inferred from direct assay
10362251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lin-7 homolog C

mammalian lin-seven protein 3

veli-3 protein

vertebrate lin-7 homolog 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07678 LIN7C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lin7c NCBI NCBI:55327