Xylt1 - xylosyltransferase 1 Gene

Also Known as Xt1; XYLT-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64133

Summary

Predicted to enable protein xylosyltransferase activity. Involved in negative regulation of axon regeneration; proteoglycan biosynthetic process; and response to interleukin-1. Predicted to be located in Golgi cis cisterna; Golgi membrane; and extracellular space. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Orthologous to human XYLT1 (xylosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Xylt1 Products (1)

mRNA Protein Name
NM_022295.2 NP_071631.1 xylosyltransferase 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of axon regeneration IMP
IMP: Inferred from mutant phenotype
18765417 RGD
involved in proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
19001053 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
19001053 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

xylosyltransferase 1

  • peptide O-xylosyltransferase 1

  • xylosyltransferase I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15907 XYLT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xylt1 NCBI NCBI:64131