2. Gene
  3. Xylt1 - xylosyltransferase 1 Gene

Xylt1 - xylosyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Xt1; XYLT-1

Gene ID: 64133 | Gene type: protein coding

About Xylt1

Summary

Predicted to enable protein xylosyltransferase activity. Involved in negative regulation of axon regeneration; proteoglycan biosynthetic process; and response to interleukin-1. Predicted to be located in Golgi cis cisterna; Golgi membrane; and extracellular space. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Orthologous to human XYLT1 (xylosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Xylt1 Products(1)

mRNA Protein Name
NM_022295.2 NP_071631.1 xylosyltransferase 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of axon regeneration IMP
IMP: Inferred from mutant phenotype
18765417 RGD
involved in proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
19001053 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
19001053 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

xylosyltransferase 1

peptide O-xylosyltransferase 1

xylosyltransferase I

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15907 XYLT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xylt1 NCBI NCBI:64131