Ctsz - cathepsin Z Gene

Also Known as CTSX; D2Wsu143e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64138

Summary

This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate a mature enzyme with Carboxypeptidase activity. An enzymatically inactive form of the protein, that is associated with the propeptide, may be involved in Cancer cell invasion and proliferation. Homozygous knockout mice for this gene exhibit impaired Cancer cell invasion in a breast Cancer model. [provided by RefSeq, Aug 2015]

Ctsz Products (1)

mRNA Protein Name
NM_022325.5 NP_071720.1 cathepsin Z preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in epithelial tube branching involved in lung morphogenesis IEP
IEP: Inferred from expression pattern
17500053 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cathepsin Z

  • cathepsin X

Recombinant Ctsz Proteins

Cat. No. Product Name Accession Purity
HY-P75448 Cathepsin Z/CTSZ Protein, Mouse (HEK293, His) Q9WUU7 (A23-V306) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03349 CTSZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17881 Ctsz Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24350 Ctsz Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsz NCBI NCBI:1522