Mllt1 - myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 Gene

Also Known as ENL; BAM11; LTG19

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64144

Summary

Acts upstream of or within negative regulation of protein kinase activity. Located in nucleus. Is expressed in several structures, including brain; branchial arch; limb; maxillary process; and sensory organ. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit). [provided by Alliance of Genome Resources, Apr 2022]

Mllt1 Products (3)

mRNA Protein Name
NM_001410196.1 NP_001397125.1 protein ENL isoform 2
NM_001410198.1 NP_001397127.1 protein ENL isoform 3
NM_022328.3 NP_071723.1 protein ENL isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11007757 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of protein kinase activity IDA
IDA: Inferred from direct assay
11007757 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11007757 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein ENL

  • leukemia-associated protein MLLT1

  • myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog

  • myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog

  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

  • tr

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112804 SGC-iMLLT Inhibitor 99.33% Unkown
HY-155412 PFI-6 99.91% Unkown
HY-160287 NVS MLLT-1 Inhibitor 99.79% Unkown
HY-181834 PROTAC MLLT1 Degrader-1 Degrader / Unkown
HY-184342 SYC-2863 / Unkown
HY-RS08493 MLLT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176821 PFI-6N / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mllt1 NCBI NCBI:4298