Chrna9 - cholinergic receptor nicotinic alpha 9 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65024

Summary

Enables acetylcholine-gated cation-selective channel activity. Involved in negative regulation of ERK1 and ERK2 cascade and sensory perception of sound. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse. Is integral component of postsynaptic specialization membrane. Orthologous to human CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna9 Products (1)

mRNA Protein Name
NM_022930.2 NP_075219.2 neuronal acetylcholine receptor subunit alpha-9 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: Inferred from direct assay
7954834 RGD
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential EXP
EXP: Inferred from Experiment
10875922 RGD
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
10875922 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
20505147 RGD
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
12401316 RGD
is active in cholinergic synapse EXP
EXP: Inferred from Experiment
10875922 RGD
is active in cholinergic synapse IDA
IDA: Inferred from direct assay
10875922 RGD
is active in postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
18420419 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit alpha-9

  • NACHR alpha-9

  • acetylcholine receptor alpha 9 subunit (nAChR)

  • cholinergic receptor, nicotinic, alpha 9 (neuronal)

  • cholinergic receptor, nicotinic, alpha polypeptide 9

  • nicotinic acetylcholine receptor subunit alpha-9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02673 CHRNA9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrna9 NCBI NCBI:55584