Slc2a5 - solute carrier family 2 member 5 Gene

Rattus norvegicus

Gene ID: 65197 | Gene type: protein coding

About Slc2a5

Summary

Enables fructose binding activity; fructose transmembrane transporter activity; and glucose transmembrane transporter activity. Involved in cellular response to fructose stimulus; fructose import across plasma membrane; and glucose transmembrane transport. Located in sarcolemma. Is integral component of plasma membrane. Orthologous to human SLC2A5 (solute carrier family 2 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a5 Products(1)

mRNA	Protein	Name
NM_031741.1	NP_113929.1	solute carrier family 2, facilitated glucose transporter member 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables D-glucose transmembrane transporter activity	IDA IDA: Inferred from direct assay	8333543	RGD
enables fructose binding	IDA IDA: Inferred from direct assay	26416735	RGD
enables fructose transmembrane transporter activity	IDA IDA: Inferred from direct assay	8333543	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in D-glucose transmembrane transport	IDA IDA: Inferred from direct assay	8333543	RGD
involved in cellular response to fructose stimulus	IDA IDA: Inferred from direct assay	9820812	RGD
involved in fructose import across plasma membrane	IDA IDA: Inferred from direct assay	8333543	RGD
involved in fructose transmembrane transport	IDA IDA: Inferred from direct assay	8333543	RGD
involved in fructose transmembrane transport	IEP IEP: Inferred from expression pattern	11518678	RGD
involved in metanephric proximal tubule development	IEP IEP: Inferred from expression pattern	30645697	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	8333543	RGD
located in sarcolemma	IDA IDA: Inferred from direct assay	9820812	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

solute carrier family 2, facilitated glucose transporter member 5

GLUT-5	fructose transporter
glucose transporter type 5, small intestine	solute carrier family 2 (facilitated glucose transporter), member 5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13174	SLC2A5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc2a5	NCBI	NCBI:6518

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