Dpysl5 - dihydropyrimidinase-like 5 Gene

Also Known as CRAM; Crmp5; CRMP-5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65254

Summary

Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds and microtubule binding activity. Predicted to be involved in nervous system development. Predicted to act upstream of or within axon guidance. Located in cytoplasm; dendrite; and neuronal cell body. Is expressed in brain; cerebral cortex marginal layer; cerebral cortex marginal zone; and cortical plate. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Orthologous to human DPYSL5 (dihydropyrimidinase like 5). [provided by Alliance of Genome Resources, Apr 2022]

Dpysl5 Products (3)

mRNA Protein Name
NM_001356948.1 NP_001343877.1 dihydropyrimidinase-related protein 5 isoform a
NM_001356949.1 NP_001343878.1 dihydropyrimidinase-related protein 5 isoform b
NM_023047.3 NP_075534.1 dihydropyrimidinase-related protein 5 isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10956643 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IPI
IPI: Inferred from physical interaction
11069615 MGI
located in dendrite IDA
IDA: Inferred from direct assay
15834957 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
31171447 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15834957 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in synapse IMP
IMP: Inferred from mutant phenotype
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dihydropyrimidinase-related protein 5

  • DRP-5

  • collapsin response mediator protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03984 DPYSL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dpysl5 NCBI NCBI:56896