GPR89A - G protein-coupled receptor 89A Gene

Also Known as GPHR; GPR89; SH120; GPR89B; UNQ192

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 653519

About GPR89A

Cytogenetic location: 1q21.1 Genomic coordinates (GRCh38): 1:145,607,988-145,670,650 (from NCBI)

This gene has 13 transcripts (splice variants), 201 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 15.4), testis (RPKM 12.4) and 25 other tissues.

Summary

GPR89A is a nearly identical copy of the GPR89B gene (MIM 612806).[supplied by OMIM, Jun 2009]

GPR89A Products (2)

mRNA Protein Name
NM_001097612.2 NP_001091081.1 Golgi pH regulator A isoform 1
NM_001097613.3 NP_001091082.2 Golgi pH regulator A isoform 2

GPR89A Protein Structure

GPHR_N

GPHR_N: The Golgi pH Regulator (GPHR) Family N-terminal (138 - 207)

ABA_GPCR

ABA_GPCR: Abscisic acid G-protein coupled receptor (273 - 447)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 455 a.a.
Protein Preferred Names Protein Names

Golgi pH regulator A

  • protein GPR89

GPR89A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GPR89B P0CG08 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
GPR89B P0CG08 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
GPR89B P0CG08 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hemochromatosis, Type 2a

  • Hemochromatosis Type 2a

  • HFE2A

  • Juvenile Hemochromatosis

  • Hemochromatosis 2a

  • Hefe2

  • Hemochromatosis Type 2

  • Jh
Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb

  • Chromosome 1q21.1 Deletion Syndrome

  • 1q21.1 Microdeletion Syndrome

  • Monosomy 1q21.1

  • 1q21.1 Microdeletion

  • Chromosome 1q21.1 Microdeletion Syndrome

  • 1q21.1 Contiguous Gene Deletion

  • 1q21.1 Deletion

  • Del(1)(Q21)

  • 1q21.1 Deletion Syndrome
Thrombocytopenia-Absent Radius Syndrome

  • Tar Syndrome

  • Radial Aplasia-Thrombocytopenia Syndrome

  • Absent Radii And Thrombocytopenia

  • TAR

  • Chromosome 1q21.1 Deletion Syndrome, 200-Kb

  • Thrombocytopenia Absent Radius Syndrome

  • Thrombocytopenia Absent Radii

  • Chromosome 1q21.1 Deletion Syndrome

  • Thrombocytopenia With Absent Radii Syndrome

  • Radial Aplasia-Amegakaryocytic Thrombocytopenia
Duodenal Atresia

  • Duodenal Stenosis

  • Familial Duodenal Atresia
Chromosome 1p36 Deletion Syndrome

  • 1p36 Deletion Syndrome

  • Deletion 1p36

  • Monosomy 1p36

  • Subtelomeric 1p36 Deletion

  • Monosomy 1p36 Syndrome

  • Distal Monosomy 1p36

  • Del(1)(P36)

  • Deletion 1pter

  • Monosomy 1pter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05746 GPR89A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GPR89A MGD MGI:1914799