Maco1 - macoilin 1 Gene

Also Known as C61; Tmem57; 1110007C24Rik; 9230118A01Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 66146

Summary

Predicted to enable microtubule binding activity. Acts upstream of or within brain development. Located in several cellular components, including axon; neuron projection terminus; and nuclear membrane. Orthologous to human MACO1 (macoilin 1). [provided by Alliance of Genome Resources, Apr 2022]

Maco1 Products (4)

mRNA	Protein	Name
NM_001355499.1	NP_001342428.1	macoilin isoform 2
NM_001355500.1	NP_001342429.1	macoilin isoform 3
NM_001355501.1	NP_001342430.1	macoilin isoform 3
NM_025382.6	NP_079658.2	macoilin isoform 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
involved in brain development	IEP IEP: Inferred from expression pattern	15255972	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in axon	IDA IDA: Inferred from direct assay	15255972	MGI
located in neuron projection	IDA IDA: Inferred from direct assay	15255972	MGI
located in neuron projection terminus	IDA IDA: Inferred from direct assay	15255972	MGI
located in nuclear membrane	IDA IDA: Inferred from direct assay	15255972	MGI
located in nucleus	IDA IDA: Inferred from direct assay	12459264	MGI
located in synapse	IDA IDA: Inferred from direct assay	15255972	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
macoilin	brain-specific adapter protein C61 brain-specific adaptor protein C61 transmembrane protein 57

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07944	MACO1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Maco1	NCBI	NCBI:55219