SOX15 - SRY-box transcription factor 15 Gene

Also Known as SOX20; SOX26; SOX27

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6665

About SOX15

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,588,178-7,590,094 (from NCBI)

This gene has 3 transcripts (splice variants), 281 orthologues and 20 paralogues. Biased expression in skin (RPKM 12.3), esophagus (RPKM 6.9) and 8 other tissues.

Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with Other proteins. [provided by RefSeq, Jul 2008]

SOX15 Products (1)

mRNA Protein Name
NM_006942.2 NP_008873.1 protein SOX-15

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SOX15 Protein Structure

HMG_box

HMG_box: HMG (high mobility group) box (49 - 117)

  • 0
  • 100
  • 200
  • 233 a.a.
Protein Preferred Names Protein Names

protein SOX-15

  • SRY (sex determining region Y)-box 15

SOX15 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810237 Sox-15 Antibody (YA9581) WB, ICC/IF, IF-Tissue, IP, ELISA human
HY-P811339 SOX15 Antibody WB, IHC-P Human, Mouse

Related Diseases

Diseases Alias
Acromesomelic Dysplasia 2a

  • Chondrodysplasia, Grebe Type

  • Acromesomelic Dysplasia, Grebe Type

  • Grebe Chondrodysplasia

  • Amdg

  • Grebe Syndrome

  • AMD2A

  • Grebe Dysplasia

  • Achondrogenesis, Brazilian

  • Achondrogenesis, Type Ii, Formerly

  • Acromesomelic Dysplasia-2a

  • Achondrogenesis Type Ii

  • Brazilian Achondrogenesis

  • Acromesomelic Chondrodysplasia, Grebe Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13588 SOX15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22815 Sox15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29330 Sox15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SOX15 MGD MGI:98363
Macaca mulatta SOX15 VGNC VGNC:104658
Bos taurus SOX15 VGNC VGNC:35143
Felis catus SOX15 VGNC VGNC:65580
Rattus norvegicus SOX15 RGD RGD:1312022
Canis familiaris SOX15 VGNC VGNC:46675
Others SOX15 NCBI