Rffl - ring finger and FYVE like domain containing protein Gene

Also Known as Carp2; 1700051E09Rik; 4930516L10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67338

Summary

Predicted to enable enzyme binding activity; p53 binding activity; and ubiquitin protein Ligase activity. Involved in regulation of fibroblast migration. Acts upstream of or within intracellular protein transport. Located in cytoplasmic vesicle. Is expressed in bladder; retina inner nuclear layer; retina outer nuclear layer; and ureter. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Rffl Products (5)

mRNA Protein Name
NM_001007465.3 NP_001007466.1 E3 ubiquitin-protein ligase rififylin isoform 1
NM_001164569.1 NP_001158041.1 E3 ubiquitin-protein ligase rififylin isoform 3
NM_001164570.1 NP_001158042.1 E3 ubiquitin-protein ligase rififylin isoform 4
NM_001164571.1 NP_001158043.1 E3 ubiquitin-protein ligase rififylin isoform 5
NM_026097.3 NP_080373.1 E3 ubiquitin-protein ligase rififylin isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within intracellular protein transport IDA
IDA: Inferred from direct assay
15229288 MGI
involved in regulation of fibroblast migration IMP
IMP: Inferred from mutant phenotype
22609986 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
15229288 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase rififylin

  • RING finger and FYVE-like domain-containing protein 1

  • RING-type E3 ubiquitin transferase rififylin

  • fring

  • rififylin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11871 RFFL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rffl NCBI NCBI:117584