2. Gene
  3. Eqtn - equatorin, sperm acrosome associated Gene

Eqtn - equatorin, sperm acrosome associated Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Afaf; Eqtl; Eqts; 1700028B15Rik; 4930579C15Rik

Gene ID: 67753 | Gene type: protein coding

About Eqtn

Summary

Acts upstream of or within acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Located in several cellular components, including acrosomal membrane; early endosome; and nucleus. Orthologous to human EQTN (equatorin). [provided by Alliance of Genome Resources, Apr 2022]

Eqtn Products(2)

mRNA Protein Name
NM_001290623.1 NP_001277552.1 equatorin isoform 2 precursor
NM_027089.4 NP_081365.2 equatorin isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19285662 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within acrosomal vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
19285662 MGI
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
19285662 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
19285662 MGI
acts upstream of or within fusion of sperm to egg plasma membrane involved in single fertilization IMP
IMP: Inferred from mutant phenotype
9674989 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16831425 MGI
located in early endosome IDA
IDA: Inferred from direct assay
16831425 MGI
located in inner acrosomal membrane IDA
IDA: Inferred from direct assay
19605790 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16831425 MGI
located in outer acrosomal membrane IDA
IDA: Inferred from direct assay
19605790 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16831425 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

equatorin

MN9 antigen

acrosome formation associated factor

sperm-specific single transmembrane domain protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04461 EQTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29489 Eqtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eqtn NCBI NCBI:54586