Eqtn - equatorin, sperm acrosome associated Gene

Also Known as Afaf; Eqtl; Eqts; 1700028B15Rik; 4930579C15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67753

Summary

Acts upstream of or within acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Located in several cellular components, including acrosomal membrane; early endosome; and nucleus. Orthologous to human EQTN (equatorin). [provided by Alliance of Genome Resources, Apr 2022]

Eqtn Products (2)

mRNA Protein Name
NM_001290623.1 NP_001277552.1 equatorin isoform 2 precursor
NM_027089.4 NP_081365.2 equatorin isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19285662 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within acrosomal vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
19285662 MGI
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
19285662 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
19285662 MGI
acts upstream of or within fusion of sperm to egg plasma membrane involved in single fertilization IMP
IMP: Inferred from mutant phenotype
9674989 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16831425 MGI
located in early endosome IDA
IDA: Inferred from direct assay
16831425 MGI
located in inner acrosomal membrane IDA
IDA: Inferred from direct assay
19605790 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16831425 MGI
located in outer acrosomal membrane IDA
IDA: Inferred from direct assay
19605790 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16831425 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

equatorin

  • MN9 antigen

  • acrosome formation associated factor

  • sperm-specific single transmembrane domain protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04461 EQTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29489 Eqtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eqtn NCBI NCBI:54586