Sdf2l1 - stromal cell-derived factor 2-like 1 Gene

Rattus norvegicus

Gene ID: 680945 | Gene type: protein coding

About Sdf2l1

Summary

Enables ATPase binding activity; chaperone binding activity; and misfolded protein binding activity. Acts upstream of or within ER-associated misfolded protein catabolic process and regulation of apoptotic process. Located in endoplasmic reticulum and membrane. Used to study type 2 diabetes mellitus. Orthologous to human SDF2L1 (stromal cell derived factor 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Sdf2l1 Products(1)

mRNA	Protein	Name
NM_001109433.1	NP_001102903.1	stromal cell-derived factor 2-like protein 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATPase binding	IDA IDA: Inferred from direct assay	23444373	RGD
enables misfolded protein binding	IDA IDA: Inferred from direct assay	23444373	RGD
enables protein-folding chaperone binding	IDA IDA: Inferred from direct assay	23444373	RGD

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within ERAD pathway	IMP IMP: Inferred from mutant phenotype	23444373	RGD
acts upstream of or within cellular response to misfolded protein	IDA IDA: Inferred from direct assay	23444373	RGD
acts upstream of or within regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	23444373	RGD
acts upstream of or within response to endoplasmic reticulum stress	IDA IDA: Inferred from direct assay	23444373	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	23444373	RGD
located in membrane	IDA IDA: Inferred from direct assay	23444373	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

stromal cell-derived factor 2-like protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12588	SDF2L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sdf2l1	NCBI	NCBI:23753

Name
Email *

	Sorry, but the email address you supplied was invalid.