SDF2L1 - stromal cell derived factor 2 like 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23753

About SDF2L1

Cytogenetic location: 22q11.21 Genomic coordinates (GRCh38): 22:21,642,302-21,644,299 (from NCBI)

This gene has 2 transcripts (splice variants), 204 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 15.5), stomach (RPKM 14.1) and 25 other tissues.

Summary

Enables misfolded protein binding activity. Involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum. Part of chaperone complex. [provided by Alliance of Genome Resources, Apr 2022]

SDF2L1 Products (1)

mRNA Protein Name
NM_022044.3 NP_071327.2 stromal cell-derived factor 2-like protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables misfolded protein binding IDA
IDA: Inferred from direct assay
28597544 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in chaperone cofactor-dependent protein refolding IMP
IMP: Inferred from mutant phenotype
28597544 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
28597544 GOA
part of protein folding chaperone complex IPI
IPI: Inferred from physical interaction
28597544 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SDF2L1 Protein Structure

MIR

MIR: MIR domain (53 - 197)

  • 0
  • 100
  • 200
  • 221 a.a.
Protein Preferred Names Protein Names

stromal cell-derived factor 2-like protein 1

  • PWP1-interacting protein 8

SDF2L1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SDF2L1 Q9HCN8 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
SDF2L1 Q9HCN8 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
SDF2L1 Q9HCN8 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
SDF2L1 Q9HCN8 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12588 SDF2L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SDF2L1 VGNC VGNC:52966
Rattus norvegicus SDF2L1 RGD RGD:1585844
Felis catus SDF2L1 VGNC VGNC:80481
Bos taurus SDF2L1 VGNC VGNC:34386
Mus musculus SDF2L1 MGD MGI:2149842
Macaca mulatta SDF2L1 VGNC VGNC:98442
Others SDF2L1 NCBI