2. Gene
  3. PAK1 - p21 (RAC1) activated kinase 1 Gene

PAK1 - p21 (RAC1) activated kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 698585 | Gene type: protein coding

About PAK1

Primary_assembly 14: 70,352,631-70,666,946 reverse strand.Mmul_10:CM014349.1

This gene has 10 transcripts (splice variants), 217 orthologues and 35 paralogues.

PAK1 Products(19)

mRNA Protein Name
XM_028833849.1 XP_028689682.1 serine/threonine-protein kinase PAK 1 isoform X3
XM_028833853.1 XP_028689686.1 serine/threonine-protein kinase PAK 1 isoform X5
XM_028833851.1 XP_028689684.1 serine/threonine-protein kinase PAK 1 isoform X5
XM_015115258.2 XP_014970744.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_028833856.1 XP_028689689.1 serine/threonine-protein kinase PAK 1 isoform X8
XM_028833854.1 XP_028689687.1 serine/threonine-protein kinase PAK 1 isoform X6
XM_015115256.2 XP_014970742.2 serine/threonine-protein kinase PAK 1 isoform X5
XM_028833852.1 XP_028689685.1 serine/threonine-protein kinase PAK 1 isoform X5
XM_015115261.2 XP_014970747.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_028833855.1 XP_028689688.1 serine/threonine-protein kinase PAK 1 isoform X7
XM_015115262.2 XP_014970748.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_028833857.1 XP_028689690.1 serine/threonine-protein kinase PAK 1 isoform X8
XM_028833850.1 XP_028689683.1 serine/threonine-protein kinase PAK 1 isoform X4
XM_015115263.2 XP_014970749.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_015115266.2 XP_014970752.2 serine/threonine-protein kinase PAK 1 isoform X5
XM_015115265.2 XP_014970751.2 serine/threonine-protein kinase PAK 1 isoform X5
XM_015115260.2 XP_014970746.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_015115264.2 XP_014970750.2 serine/threonine-protein kinase PAK 1 isoform X1
XM_028833848.1 XP_028689681.1 serine/threonine-protein kinase PAK 1 isoform X2

PAK1 Protein Structure

PBD

PBD: pfam00786 (73 - 131)

STKc_PAK1

STKc_PAK1: cd06654 (269 - 564)

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  • 566 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PAK 1

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12005 Fingolimod hydrochloride Activator 99.94% Yes
HY-15027 5-Aminosalicylic Acid Inhibitor 99.97% Unkown
HY-11063 Fingolimod Activator 99.97% Yes
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-13007 PF-3758309 Inhibitor 99.79% Phase 1
HY-13007B PF-3758309 dihydrochloride Inhibitor / Phase 1
HY-13007A PF-3758309 hydrochloride Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15663 IPA-3 Inhibitor 99.39% Unkown
HY-15542A FRAX597 Inhibitor 99.36% Unkown
HY-15542B FRAX486 Inhibitor 98.10% Unkown
HY-19635 G-5555 Inhibitor 99.88% Unkown
HY-19538 FRAX1036 Inhibitor 98.88% Unkown
HY-120940 AZ13705339 Inhibitor 98.57% Unkown
HY-19635A G-5555 hydrochloride Inhibitor 98.26% Unkown
HY-131043 NVS-PAK1-C Inhibitor 99.2% Unkown
HY-120940A AZ13705339 hemihydrate Inhibitor 99.77% Unkown
HY-119216 AZ13711265 Inhibitor / Unkown
HY-146681 PAK1-IN-1 Inhibitor / Unkown
HY-164534 SIK2/3-IN-2 Inhibitor / Unkown
HY-110085 2,2′-Dihydroxy-6,6′-dinaphthyl disulfide Inhibitor 98.49% Unkown
HY-131265 Mesalamine impurity P Inhibitor / Unkown
HY-182357 PAK1-IN-3 Inhibitor / Unkown
HY-116917 G-9791 Inhibitor / Unkown
HY-146786 ZMF-10 Inhibitor / Unkown
HY-159897 PAK4-IN-5 Inhibitor / Unkown
HY-146783 ZINC194100678 Inhibitor / Unkown
HY-176539 PAK1-IN-2 Inhibitor / Unkown
HY-164374 AK963/40708899 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAK1 NCBI NCBI:5058