Gdpd2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

Also Known as Gde3; Obdpf; 9130017L10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71584

Summary

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. Overexpression of this gene is associated with activity-dependent actin Cytoskeleton disorganization. The encoded protein may negatively regulate growth rate and induce differentiation of osteoblasts. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Gdpd2 Products (3)

mRNA Protein Name
NM_001305941.1 NP_001292870.1 glycerophosphoinositol inositolphosphodiesterase GDPD2
NM_001358507.1 NP_001345436.1 glycerophosphoinositol inositolphosphodiesterase GDPD2
NM_023608.4 NP_076097.1 glycerophosphoinositol inositolphosphodiesterase GDPD2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament organization IDA
IDA: Inferred from direct assay
12933806 MGI
acts upstream of or within positive regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
12933806 MGI
acts upstream of or within positive regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
12933806 MGI
Cellular Component GO Annotation Evidence References Source
located in actin filament IDA
IDA: Inferred from direct assay
12933806 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
12933806 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12933806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerophosphoinositol inositolphosphodiesterase GDPD2

  • glycerophosphodiester phosphodiesterase 3

  • osteoblast differentiation promoting factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05363 GDPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdpd2 NCBI NCBI:54857