2. Gene
  3. Gdpd2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

Gdpd2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gde3; Obdpf; 9130017L10Rik

Gene ID: 71584 | Gene type: protein coding

About Gdpd2

Summary

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. Overexpression of this gene is associated with activity-dependent actin Cytoskeleton disorganization. The encoded protein may negatively regulate growth rate and induce differentiation of osteoblasts. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Gdpd2 Products(3)

mRNA Protein Name
NM_001305941.1 NP_001292870.1 glycerophosphoinositol inositolphosphodiesterase GDPD2
NM_001358507.1 NP_001345436.1 glycerophosphoinositol inositolphosphodiesterase GDPD2
NM_023608.4 NP_076097.1 glycerophosphoinositol inositolphosphodiesterase GDPD2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within actin filament organization IDA
IDA: Inferred from direct assay
12933806 MGI
acts upstream of or within positive regulation of osteoblast differentiation IDA
IDA: Inferred from direct assay
12933806 MGI
acts upstream of or within positive regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
12933806 MGI
Cellular Component GO Annotation Evidence Reference Source
located in actin filament IDA
IDA: Inferred from direct assay
12933806 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
12933806 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12933806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerophosphoinositol inositolphosphodiesterase GDPD2

glycerophosphodiester phosphodiesterase 3

osteoblast differentiation promoting factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05363 GDPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdpd2 NCBI NCBI:54857