Syde1 - synapse defective 1, Rho GTPase, homolog 1 (C. elegans) Gene

Also Known as mSYD1A; 1200008N06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71709

Summary

Enables GTPase activator activity. Acts upstream of or within several processes, including labyrinthine layer blood vessel development; synaptic vesicle docking; and synaptonemal complex assembly. Located in cerebellar mossy fiber; cytosol; and synaptic membrane. Is expressed in labyrinthine zone; placenta; spongiotrophoblast; trophectoderm; and trophoblast giant cell. Orthologous to human SYDE1 (synapse defective Rho GTPase homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Syde1 Products (1)

mRNA Protein Name
NM_027875.1 NP_082151.1 rho GTPase-activating protein SYDE1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
23791195 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23791195 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
23791195 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: Inferred from mutant phenotype
27917469 MGI
acts upstream of or within labyrinthine layer development IMP
IMP: Inferred from mutant phenotype
27917469 MGI
acts upstream of or within positive regulation of synaptic transmission IMP
IMP: Inferred from mutant phenotype
23791195 MGI
acts upstream of or within regulation of Ras protein signal transduction IMP
IMP: Inferred from mutant phenotype
27917469 MGI
acts upstream of or within synaptic vesicle docking IMP
IMP: Inferred from mutant phenotype
23791195 MGI
acts upstream of or within synaptonemal complex assembly IMP
IMP: Inferred from mutant phenotype
23791195 MGI
Cellular Component GO Annotation Evidence References Source
located in cerebellar mossy fiber IDA
IDA: Inferred from direct assay
23791195 MGI
located in cytosol IDA
IDA: Inferred from direct assay
23791195 MGI
located in synaptic membrane IDA
IDA: Inferred from direct assay
23791195 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein SYDE1

  • protein syd-1 homolog 1

  • synapse defective protein 1 homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14073 SYDE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Syde1 NCBI NCBI:85360