Syde1 - synapse defective 1, Rho GTPase, homolog 1 (C. elegans) Gene

Mus musculus

Also known as mSYD1A; 1200008N06Rik

Gene ID: 71709 | Gene type: protein coding

About Syde1

Summary

Enables GTPase activator activity. Acts upstream of or within several processes, including labyrinthine layer blood vessel development; synaptic vesicle docking; and synaptonemal complex assembly. Located in cerebellar mossy fiber; cytosol; and synaptic membrane. Is expressed in labyrinthine zone; placenta; spongiotrophoblast; trophectoderm; and trophoblast giant cell. Orthologous to human SYDE1 (synapse defective Rho GTPase homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Syde1 Products(1)

mRNA	Protein	Name
NM_027875.1	NP_082151.1	rho GTPase-activating protein SYDE1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activator activity	IDA IDA: Inferred from direct assay	23791195	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	23791195	MGI
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	23791195	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within labyrinthine layer blood vessel development	IMP IMP: Inferred from mutant phenotype	27917469	MGI
acts upstream of or within labyrinthine layer development	IMP IMP: Inferred from mutant phenotype	27917469	MGI
acts upstream of or within positive regulation of synaptic transmission	IMP IMP: Inferred from mutant phenotype	23791195	MGI
acts upstream of or within regulation of Ras protein signal transduction	IMP IMP: Inferred from mutant phenotype	27917469	MGI
acts upstream of or within synaptic vesicle docking	IMP IMP: Inferred from mutant phenotype	23791195	MGI
acts upstream of or within synaptonemal complex assembly	IMP IMP: Inferred from mutant phenotype	23791195	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cerebellar mossy fiber	IDA IDA: Inferred from direct assay	23791195	MGI
located in cytosol	IDA IDA: Inferred from direct assay	23791195	MGI
located in synaptic membrane	IDA IDA: Inferred from direct assay	23791195	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

rho GTPase-activating protein SYDE1

protein syd-1 homolog 1

synapse defective protein 1 homolog 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14073	SYDE1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Syde1	NCBI	NCBI:85360

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