Tysnd1 - trypsin domain containing 1 Gene
Also Known as 1300019N10Rik
Species: Mus musculus
Summary
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Tysnd1 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001272090.1 | NP_001259019.1 | peroxisomal leader peptide-processing protease isoform b |
| NM_001272091.1 | NP_001259020.1 | peroxisomal leader peptide-processing protease isoform c |
| NM_001272092.1 | NP_001259021.1 | peroxisomal leader peptide-processing protease isoform d |
| NM_027912.1 | NP_082188.1 | peroxisomal leader peptide-processing protease isoform a |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables serine-type endopeptidase activity |
EXP
EXP: Inferred from Experiment
|
17255948 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
peroxisomal leader peptide-processing protease |
|