2. Gene
  3. Tysnd1 - trypsin domain containing 1 Gene

Tysnd1 - trypsin domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1300019N10Rik

Gene ID: 71767 | Gene type: protein coding

About Tysnd1

Summary

This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

Tysnd1 Products(4)

mRNA Protein Name
NM_001272090.1 NP_001259019.1 peroxisomal leader peptide-processing protease isoform b
NM_001272091.1 NP_001259020.1 peroxisomal leader peptide-processing protease isoform c
NM_001272092.1 NP_001259021.1 peroxisomal leader peptide-processing protease isoform d
NM_027912.1 NP_082188.1 peroxisomal leader peptide-processing protease isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables serine-type endopeptidase activity EXP
EXP: Inferred from Experiment
17255948 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisomal leader peptide-processing protease

trypsin domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15311 TYSND1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tysnd1 NCBI NCBI:219743