Inhca - inhibitor of carbonic anhydrase Gene

Also Known as Ica; mICA; 1300017J02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71775

Summary

This gene is a member of the transferrin gene family. Unlike many members of that gene family it does not play a significant role in iron homeostasis but rather is an inhibitor of Carbonic Anhydrase. This gene arose as a tandem duplicate of the adjacent transferrin gene sometime after the divergence of monotremes and therian mammals but before the diversification of placental mammals. This gene subsequently became a pseudogene in monkeys and apes. In lemurs and Other strepsirrhine primates it possibly remains a protein coding gene. [provided by RefSeq, Oct 2021]

Inhca Products (1)

mRNA Protein Name
NM_027918.2 NP_082194.1 inhibitor of carbonic anhydrase precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables enzyme inhibitor activity IDA
IDA: Inferred from direct assay
17511619 MGI
NOT enables iron ion binding IDA
IDA: Inferred from direct assay
18712936 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inhibitor of carbonic anhydrase

Recombinant Inhca Proteins

Cat. No. Product Name Accession Purity
HY-P73912 ICA Protein, Mouse (HEK293, His) Q9DBD0/NP_082194.1 (L20-Y700) ≥ 95%, as determined by reducing SDS-PAGE.