Cfap45 - cilia and flagella associated protein 45 Gene

Also Known as Nesg1; Ccdc19; 1700028D05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71870

Summary

Predicted to enable AMP binding activity. Acts upstream of or within epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and regulation of cilium beat frequency involved in ciliary motility. Located in 9+0 motile cilium. Is expressed in lateral ventricle choroid plexus; lung; metencephalon part of 4th ventricle choroid plexus; and olfactory epithelium. Orthologous to human CFAP45 (cilia and flagella associated protein 45). [provided by Alliance of Genome Resources, Apr 2022]

Cfap45 Products (1)

mRNA Protein Name
NM_027972.1 NP_082248.1 cilia- and flagella-associated protein 45

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
37236356 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebrospinal fluid circulation IMP
IMP: Inferred from mutant phenotype
33139725 MGI
acts upstream of or within epithelial cilium movement involved in determination of left/right asymmetry IMP
IMP: Inferred from mutant phenotype
33139725 MGI
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
33139725 MGI
acts upstream of or within regulation of cilium beat frequency involved in ciliary motility IMP
IMP: Inferred from mutant phenotype
33139725 MGI
Cellular Component GO Annotation Evidence References Source
located in 9+0 motile cilium IDA
IDA: Inferred from direct assay
33139725 MGI
is active in axonemal B tubule inner sheath IDA
IDA: Inferred from direct assay
37295417 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cilia- and flagella-associated protein 45

  • coiled-coil domain containing 19

  • coiled-coil domain-containing protein 19

  • nasopharyngeal epithelium specific protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02553 CFAP45 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cfap45 NCBI NCBI:25790