2. Gene
  3. Sars2 - seryl-aminoacyl-tRNA synthetase 2 Gene

Sars2 - seryl-aminoacyl-tRNA synthetase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SerRS; SerRSmt; D7Ertd353e; 2410015F05Rik

Gene ID: 71984 | Gene type: protein coding

About Sars2

Summary

Predicted to enable ATP binding activity; serine-tRNA Ligase activity; and tRNA binding activity. Predicted to be involved in mitochondrial seryl-tRNA aminoacylation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; eye; integumental system; nervous system; and respiratory system. Orthologous to human SARS2 (seryl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Sars2 Products(1)

mRNA Protein Name
NM_023637.3 NP_076126.2 serine--tRNA ligase, mitochondrial precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
15081407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine--tRNA ligase, mitochondrial

seryl-tRNA synthetase, mitochondrial

seryl-tRNA(Ser/Sec) synthetase

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108325 Brequinar Inhibitor 99.94% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12449 SARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-108325S Brequinar-d3 Inhibitor / Unkown
HY-180129 SARS-CoV-2-IN-120 Inhibitor / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990814 Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) Inhibitor / Unkown
HY-P990815 Anti-SARS-CoV-2 S protein Antibody (RBD epitope A, SARS2-01) Inhibitor / Unkown
HY-P990816 Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) Inhibitor / Unkown
HY-P991763 Anti-SARS-CoV-2 S protein (RBD) Antibody (SARS2-38) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sars2 NCBI NCBI:54938