Sars2 - seryl-aminoacyl-tRNA synthetase 2 Gene
Also Known as SerRS; SerRSmt; D7Ertd353e; 2410015F05Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 71984
Summary
Predicted to enable ATP binding activity; serine-tRNA Ligase activity; and tRNA binding activity. Predicted to be involved in mitochondrial seryl-tRNA aminoacylation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; eye; integumental system; nervous system; and respiratory system. Orthologous to human SARS2 (seryl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]
Sars2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_023637.3 | NP_076126.2 | serine--tRNA ligase, mitochondrial precursor |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in mitochondrion |
IDA
IDA: Inferred from direct assay
|
15081407 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine--tRNA ligase, mitochondrial |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-108325 | Brequinar | Inhibitor | 99.94% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS12449 | SARS2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-108325S | Brequinar-d3 | Inhibitor | / | Unkown |
| HY-180129 | SARS-CoV-2-IN-120 | Inhibitor | / | Unkown |
Bioactive MoleculesInhibitory Antibodies
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990814 | Anti-SARS-CoV-2 S protein Antibody (RBD epitope B, SARS2-34) | Inhibitor | / | Unkown |
| HY-P990815 | Anti-SARS-CoV-2 S protein Antibody (RBD epitope A, SARS2-01) | Inhibitor | / | Unkown |
| HY-P990816 | Anti-SARS-CoV-2 S protein Antibody (NTD, SARS2-29) | Inhibitor | / | Unkown |
| HY-P991763 | Anti-SARS-CoV-2 S protein (RBD) Antibody (SARS2-38) | Inhibitor | / | Unkown |
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