Trmu - tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase Gene

Mus musculus

Also known as Trmt1; 1110005N20Rik; 1600025P05Rik

Gene ID: 72026 | Gene type: protein coding

About Trmu

Summary

Predicted to enable ATP binding activity; sulfurtransferase activity; and tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Located in mitochondrion. Used to study liver disease. Human ortholog(s) of this gene implicated in aminoglycoside-induced deafness; infantile liver failure syndrome; and transient infantile liver failure. Orthologous to human TRMU (tRNA mitochondrial 2-thiouridylase). [provided by Alliance of Genome Resources, Apr 2022]

Trmu Products(1)

mRNA	Protein	Name
NM_028063.2	NP_082339.1	mitochondrial tRNA-specific 2-thiouridylase 1

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	14746906	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitochondrial tRNA-specific 2-thiouridylase 1

tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15097	TRMU Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trmu	NCBI	NCBI:55687

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