Wdfy3 - WD repeat and FYVE domain containing 3 Gene

Mus musculus

Also known as ALFY; BWF1; Bchs; Ggtb3; ZFYVE25; D5Ertd66e; mKIAA0993; B930017C24; 2610509D04Rik

Gene ID: 72145 | Gene type: protein coding

About Wdfy3

Summary

Enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity. Predicted to be involved in aggrephagy. Predicted to act upstream of or within Autophagy. Located in cytoplasm. Is extrinsic component of autophagosome membrane. Is expressed in central nervous system; ganglia; heart; liver; and neural retina. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Orthologous to human WDFY3 (WD repeat and FYVE domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Wdfy3 Products(1)

mRNA	Protein	Name
NM_172882.3	NP_766470.2	WD repeat and FYVE domain-containing protein 3

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	IDA IDA: Inferred from direct assay	9108238	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	15342963	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

WD repeat and FYVE domain-containing protein 3

beach domain, WD repeat and FYVE domain-containing protein 1

galactosyltransferase 3 beta 1, 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15756	WDFY3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Wdfy3	NCBI	NCBI:23001

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