Wdfy3 - WD repeat and FYVE domain containing 3 Gene

Also Known as ALFY; BWF1; Bchs; Ggtb3; ZFYVE25; D5Ertd66e; mKIAA0993; B930017C24; 2610509D04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72145

Summary

Enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity. Predicted to be involved in aggrephagy. Predicted to act upstream of or within Autophagy. Located in cytoplasm. Is extrinsic component of autophagosome membrane. Is expressed in central nervous system; ganglia; heart; liver; and neural retina. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Orthologous to human WDFY3 (WD repeat and FYVE domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Wdfy3 Products (1)

mRNA Protein Name
NM_172882.3 NP_766470.2 WD repeat and FYVE domain-containing protein 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IDA
IDA: Inferred from direct assay
9108238 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15342963 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat and FYVE domain-containing protein 3

  • beach domain, WD repeat and FYVE domain-containing protein 1

  • galactosyltransferase 3 beta 1, 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15756 WDFY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdfy3 NCBI NCBI:23001