Xpo5 - exportin 5 Gene

Also Known as Exp5; RanBp21; mKIAA1291; 2410004H11Rik; 2700038C24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72322

Summary

Enables nuclear export signal receptor activity and tRNA binding activity. Acts upstream of or within protein export from nucleus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of RISC complex and RNA nuclear export complex. Predicted to be active in cytoplasm and nucleus. Is expressed in 2-cell stage embryo; 4-cell stage embryo; and head. Human ortholog(s) of this gene implicated in breast cancer; gastrointestinal system Cancer (multiple); lung carcinoma (multiple); multiple myeloma; and primary ovarian insufficiency. Orthologous to human XPO5 (exportin 5). [provided by Alliance of Genome Resources, Apr 2022]

Xpo5 Products (1)

mRNA Protein Name
NM_028198.3 NP_082474.1 exportin-5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables nuclear export signal receptor activity IDA
IDA: Inferred from direct assay
12426392 MGI
enables tRNA binding IDA
IDA: Inferred from direct assay
12426392 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein export from nucleus IDA
IDA: Inferred from direct assay
12426392 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exportin-5

  • ran-binding protein 21

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15891 XPO5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xpo5 NCBI NCBI:57510