2. Gene
  3. Mir107 - microRNA 107 Gene

Mir107 - microRNA 107 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn107; mir-107; mmu-mir-107

Gene ID: 723826 | Gene type: ncRNA

About Mir107

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18762567 MGI
acts upstream of or within miRNA-mediated post-transcriptional gene silencing IDA
IDA: Inferred from direct assay
21415270 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
24205035 MGI
acts upstream of or within response to oxygen levels IDA
IDA: Inferred from direct assay
18723672 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00057 hsa-miR-107 mimic 95.24% Unkown
HY-RI00057 hsa-miR-107 inhibitor 97.55% Unkown
HY-R00057A hsa-miR-107 agomir 96.13% Unkown
HY-RI00057A hsa-miR-107 antagomir 99.60% Unkown
HY-R02570 mmu-miR-107-5p mimic / Unkown
HY-R02570A mmu-miR-107-5p agomir / Unkown
HY-R04210 rno-miR-107-5p mimic / Unkown
HY-R04210A rno-miR-107-5p agomir / Unkown
HY-RI02570 mmu-miR-107-5p inhibitor / Unkown
HY-RI02570A mmu-miR-107-5p antagomir / Unkown
HY-RI04210 rno-miR-107-5p inhibitor / Unkown
HY-RI04210A rno-miR-107-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir107 NCBI NCBI:406901