2. Gene
  3. Mir375 - microRNA 375 Gene

Mir375 - microRNA 375 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn375; mir-375; mmu-mir-375

Gene ID: 723900 | Gene type: ncRNA

About Mir375

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within type B pancreatic cell development IDA
IDA: Inferred from direct assay
17804764 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI00834 hsa-miR-375-3p inhibitor 99.08% Unkown
HY-R00834 hsa-miR-375-3p mimic 97.66% Unkown
HY-R00834A hsa-miR-375-3p agomir / Unkown
HY-R00835 hsa-miR-375-5p mimic / Unkown
HY-R00835A hsa-miR-375-5p agomir / Unkown
HY-R03106 mmu-miR-375-5p mimic / Unkown
HY-R03106A mmu-miR-375-5p agomir / Unkown
HY-RI00834A hsa-miR-375-3p antagomir / Unkown
HY-RI00835 hsa-miR-375-5p inhibitor / Unkown
HY-RI00835A hsa-miR-375-5p antagomir / Unkown
HY-RI03106 mmu-miR-375-5p inhibitor / Unkown
HY-RI03106A mmu-miR-375-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir375 NCBI NCBI:494324