2. Gene
  3. Mir98 - microRNA 98 Gene

Mir98 - microRNA 98 Gene

  • Gene
  • Agent
  • Ortholog
Mus musculus

Also known as Mirn98; mir-98; mmu-mir-98

Gene ID: 723947 | Gene type: ncRNA

About Mir98

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
21609717 MGI
acts upstream of or within long-term synaptic potentiation IEP
IEP: Inferred from expression pattern
25858512 MGI
acts upstream of or within negative regulation of interleukin-10 production IDA
IDA: Inferred from direct assay
21609717 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
21609717 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI02543 hsa-miR-98-5p inhibitor 96.95% Unkown
HY-R02543 hsa-miR-98-5p mimic 99.21% Unkown
HY-R02540 hsa-miR-98-3p mimic / Unkown
HY-R02540A hsa-miR-98-3p agomir / Unkown
HY-R02543A hsa-miR-98-5p agomir / Unkown
HY-R04201 mmu-miR-98-3p mimic / Unkown
HY-R04201A mmu-miR-98-3p agomir / Unkown
HY-R04598 rno-miR-98-3p mimic / Unkown
HY-R04598A rno-miR-98-3p agomir / Unkown
HY-RI02540 hsa-miR-98-3p inhibitor / Unkown
HY-RI02540A hsa-miR-98-3p antagomir / Unkown
HY-RI02543A hsa-miR-98-5p antagomir / Unkown
HY-RI04201 mmu-miR-98-3p inhibitor / Unkown
HY-RI04201A mmu-miR-98-3p antagomir / Unkown
HY-RI04598 rno-miR-98-3p inhibitor / Unkown
HY-RI04598A rno-miR-98-3p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir98 NCBI NCBI:407054