Taf4b - TATA-box binding protein associated factor 4b Gene

Also Known as 105kDa; Taf2c2; TAFII105; TAFII-105; 2610524B04Rik; 4932409F03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72504

Summary

Predicted to enable DNA binding activity and NF-kappaB binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in positive regulation of stem cell proliferation. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of transcription factor TFIID complex. Is expressed in genitourinary system and tail. Human ortholog(s) of this gene implicated in spermatogenic failure 13. Orthologous to human TAF4B (TATA-box binding protein associated factor 4b). [provided by Alliance of Genome Resources, Apr 2022]

Taf4b Products (3)

mRNA Protein Name
NM_001100449.2 NP_001093919.1 transcription initiation factor TFIID subunit 4B isoform 1
NM_001369357.1 NP_001356286.1 transcription initiation factor TFIID subunit 4B isoform 2
NM_001369358.1 NP_001356287.1 transcription initiation factor TFIID subunit 4B isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31932482 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of stem cell proliferation IMP
IMP: Inferred from mutant phenotype
23350932 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription initiation factor TFIID subunit 4B

  • TAF(II)105

  • TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105 kDa

  • TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD

  • transcription initiation factor TFIID 105 kDa subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14170 TAF4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taf4b NCBI NCBI:6875