Exosc6 - exosome component 6 Gene

Also Known as Mtr3; C76919; 2610510N21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72544

Summary

Predicted to enable RNA binding activity. Involved in isotype switching. Acts upstream of or within positive regulation of isotype switching. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Predicted to be active in nucleolus. Is expressed in central nervous system; retina; and submandibular gland primordium. Orthologous to human EXOSC6 (exosome component 6). [provided by Alliance of Genome Resources, Apr 2022]

Exosc6 Products (1)

mRNA Protein Name
NM_028274.4 NP_082550.1 exosome complex component MTR3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in isotype switching IMP
IMP: Inferred from mutant phenotype
21255825 MGI
acts upstream of or within positive regulation of isotype switching IMP
IMP: Inferred from mutant phenotype
21255825 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exosome complex component MTR3

  • Mtr3 (mRNA transport regulator 3)-homolog

  • exosome complex exonuclease MTR3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04602 EXOSC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exosc6 NCBI NCBI:118460